UNDERSTANDING THE PATHOGENESIS AND MANAGEMENT OF AUTOIMMUNE HYPERTHYROIDISM

Authors

  • Mavlonova Nargiza 4th year student of the pediatrics faculty of the Samarkand State Medical University
  • Javbo`riyev Baxrom ]4th year student of the pediatrics faculty of the Samarkand State Medical University
  • Norbekov Navro`z 4th year student of the pediatrics faculty of the Samarkand State Medical University

Abstract

Objectives: Autoimmune hyperthyroidism, also known as Graves' disease, is a commonly diagnosed endocrine disorder resulting from the overstimulation of the thyroid gland by antibodies directed against the thyroid-stimulating hormone receptor (TSHR). The autoantibodies, known as thyroid-stimulating immunoglobulins (TSI), bind to the TSHR, leading to the excessive production of thyroid hormones, primarily triiodothyronine (T3) and thyroxine (T4). This thesis aims to provide a comprehensive review of the pathogenesis and management of autoimmune hyperthyroidism.

References

LITERATURE:

"Endocrinology: An Integrated Approach" by Stephen Nussey and Saffron Whitehead.

"The Endocrine System: An Integrated Approach" by Michael Hill.

Clinical Endocrinology and Diabetes Mellitus" by Ramzi Ajjan.

Contemporary Endocrinology" edited by Ashley Grossman.

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Published

2023-05-25