PROSPECTS FOR THE DEVELOPMENT OF PHARMACOLOGICAL PREPARATIONS BASED ON THE ANALYSIS OF THE BIOLOGICAL ACTIVITY OF KARACOLINE ALKALOID AND ITS DERIVATIVES
Keywords:
Keywords: alkaloids, drug discovery, fourth industrial revolution, quintuple helix, neglected tropical diseases, multidrug resistance, genomics, artificial intelligenceAbstract
Abstract: An overview is presented of the well-established role of alkaloids in drug discovery, the application of more sustainable chemicals, and biological approaches, and the implementation of information systems to address the current challenges faced in meeting global disease needs. The necessity for a new international paradigm for natural product discovery and development for the treatment of multidrug resistant organisms, and rare and neglected tropical diseases in the era of the Fourth Industrial Revolution and the Quintuple Helix is discussed.
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